Achieving Personal Immortality Roadmap


We created the Achieving Personal Immortality Roadmap. It represents the general view on the tasks of transhumanism. It is not enough detailed, because each line requires a larger amount of texts to explain it. At some point of time we will present the plans of action on the key points and will explain how and why they need to be implemented. Nonetheless, we believe it is important to demonstrate the comprehensive view on the problem of achieving physical immortality.

The Roadmap to Personal Immortality is list of actions that one should do to live forever. The most obvious way to reach immortality is to defeat aging, to grow and replace the diseased organs with new bioengineered ones, and in the end to be scanned into a computer. This is Plan A. It is the best possible course of events. It depends on two things – your personal actions (like regular medical checkups) and collective actions like civil activism and scientific research funding. The map is showing both paths in Plan A.

However, if Plan A fails, meaning if you die before the victory over aging, there is Plan B, which is cryonics. Some simple steps can be taken now, like calling your nearest cryocompany about a contract.

Unfortunately, cryonic could also fail, and then you can move to Plan C. Of course it is much worse – less reliable and less proven. Plan C is the so called digital immortality, that means one could be returned to life based on the existing recorded information about that person. It is a not the best plan, because we are not sure how to solve the identity problem, which will arise, and also we don’t know if collected amount of information would be enough. But it is still better than nothing.

Lastly, if Plan C fails, we have Plan D. It is not a plan in fact – it is just hope or a bet that immortality already exists somehow, maybe there is quantum immortality, or maybe the future AI will bring us back to life.

All Plans demand particular actions now – we need to prepare to all of them simultaneously. All of the Plans will lead to the same result – our minds will be uploaded into a computer and will merge with AI. So these plans are in fact multilevel defense mechanisms against death structured in the most logical way.

This map is the political program of the Longevity party – this is what we are going to do. We presented the Roadmap together with Alexei Turchin near the White House as an action to increase public attention for life extension.


Filed under Transhumanism

Civil Activism

IMG_1597 IMG_2077 IMG_1916 IMG_1911 IMG_1899 IMG_1886 IMG_1875 IMG_1873 IMG_1863 IMG_1852 IMG_1846 IMG_1803 IMG_1790 IMG_1788 IMG_1766 IMG_1750 IMG_1667 IMG_1665 IMG_1650 IMG_1615 IMG_1605

Aging is the main cause of death. Slowing down aging is an extremely complicated task that requires collaboration of hundreds of scientific labs and clinical facilities. It is not going to happen on its own. Active members of the society must signal that they are ready to fight for their right to live.

That’s why Alexei Turchin and I  came to the White House on August 16 to set an example for transhumanists of the world how one should fight for their interests. We presented the Achieving Personal Immortality Roadmap and “I demand funding for anti aging research” and “Immortality” posters. The Roadmap reflects our point of view on what each person should do to preserve their life.

We call upon everyone who shares the ideas of radical life extension to do street actions with us. Let’s do poster sessions in front of the White House, rallies, art actions, simply meet on a regular basis in bars. Join our Facebook group – Longevity Party. Together we will change the situation and will help raise enough funding for scientific research in human longevity.


1 Comment

Filed under Policy, Uncategorized

Let’s Bet on Money?


Let’s make a bet? I will propose something incredibly effective in the area of life extension and no one will be able to suggest a better strategy. Deal?

First of all, let’s think about what KPI (Key Performance Indicators) can be applied to longevity? What will tell us that we are on the right way to immortality, but not moving in the opposite direction towards the grave.

The answer here lies on the surface.

The first thing is money. The more money is invested in projects on life extesnion, the better chances we have to stay alive.

The second thing is people. There’s a nuance here. How can we count the increase in number of people? I think we need to count the most devoted supporters in the first place. There are millions of people who don’t mind living longer. Many of them run in parks or read biotechnology news, but does their activity lead to radical life extension? In my opinion, no. Moreover, having found a simple recipe like a diet, yoga or Kurzweil’s promises that everything is going to happen on its own by 2030, this kind of longevity supporters don’t do anything, because subconsciously they have already found the solution to the problem.

I propose to take only those people into account, who are involved in projects on radical human life extension. How can we identify such a person? Oh, it’s very easy. He or she talks about it explicitly and their actions are adequate, meaning they are established socially.

The third KPI is the number of events. Conferences, books, round tables, articles, social actions, 40 people going to have a beer because of the approaching singularity, youtube videos, scientific projects, movies – all of that is needed in extra large quantities.

The forth thing is the effectiveness of collaboration. This one is complicated. Perhaps the number of people involved in the same transhumanist project needs to be taken in account.

So, what strategy will be most oriented towards increasing all of the 4 indices? What can yield more money, more people, more events and more collaboration?

It is crowdfunding of scientific projects in the area of longevity. First dozens and then hundreds of crowdfunding campaigns have to be created that would raize funding for longevity gene therapy, regenerative medicine, studying molecular mechanisms of aging and their relationship to pathologies.

Yes, perhaps, we will raize not a lot of moeny in the beginning, but the projects that describe the work of the scientists, they will stay and they will continuosly owrk towards educating, promoting and attracting supporters. Moreover, they will help the universities and research institutes get government grants and venture capital.

Joint donations for longevity research will draw people closer together and will allow to constantly increase the loyal audience. There will be a chain reaction – successful crowdfunding peojects will motivate to create more projects in our field.

A set of projects on life extension will give a clear signal to the society that great things can be done to secure the main human right – the eright to live.

This is the reason why I participated in creating LabCures, because I concider this project the best strategy for the initial kick off of novel research projects including longevity.


Filed under Funding

9 Obvious Steps to Immortality


1. Use personalized medicine services. Get a lot of data about the state of your own body.

First of all, it’s various “omics”: genome, transcriptome, epigenome, proteome and metabolome. You can do a $100 23andme test, or a half million dollar analysis the way Dr. Michael Snyder from Stanford University did. He was measuring 40,000 his own biological parameters for quite a long while.

2. Participate in clinical trials of geroprotector drug candidates. Several pharmacologic drugs are now known to extend lifespan in animals. The time of human clinical trials has come. Another option for those who doesn’t want to participate themselves is to support such studies financially and organizationally.

3. Personalized science – treat your health as a scientific task. You should identify the existing and potential pathologies in your body and figure out a way to treat and prevent them.

Right now the elements of personalized science are used in treating oncological diseases: people do cancer cell genome sequencing and compare it to the genome of a healthy cell to identify what went wrong and led to the diseases. They also do experiments with the tumor by transplanting it into mice to identify the drugs that may work for the particular patient. This basically means that experiments are done to tackle the problem of a given person. To stay healthy it is a good idea to start fighting those diseases that haven’t yet manifested and try to avoid it.

4. Organize scientific research. Steve Jobs wasn’t treating his cancer during the first several months; he was relying on yoga and meditation. What he should have done was building an institute for bioengineering pancreas and liver and engage in scientific studies. There are a lot of great experiments that need to be organized, for example, studying integrated longevity gene therapy, or one can become a citizen-scientist and build a lab at home and test geroprotector candidates in old mice.

5. Be friends with people with no harmful habits, who are on low calorie diets, physically active and interested in science. Be yourself that way.

6. Create crowdfunding campaigns in the area of longevity. Researchers need a lot of money to do good science. Studies into the phenomenon of life extension and basic mechanisms of aging have paltry funding. We need to advertise the work of scientists that will save millions of lives with the help of crowdfunding platforms.

7. Increase your own competence. Knowledge quite literally extends lifespan. The mechanism of this is not clear yet, but maybe it is due to neurogenesis. New neurons are formed in our brains, but if we don’t use them to form new knowledge, they die. Perhaps it is best to study molecular biology, because this kind of knowledge can be applied to your own health.

8. Sign a cryocontract for neuropreservation and leave as much information about you as possible.

9. Promote the value of human longevity. Public opinion defines government policy. It is necessary to make the government realize the main right of every citizen – the right to live. Aging kills the majority of the people. Various social institutions have to understand this and start solving this problem.


Filed under Immortalism

What Should Be Done to Achieve Radical Life Extension?


Theoretically the problem is already solved. It is now quite obvious what kind of research should be done for life extension. For example, testing various combinations of different things that extend lifespan in old mice. Particularly important is longevity gene therapy development.

Delivering 5-7 gene vectors simultaneously carrying longevity-associated genes into an old animal could prove to be quite beneficial, because similar approach already works.

It is also clear that there are several experiments in the area of therapeutic cloning that should be done immediately.

There are about 20 other research directions in the area of radical life extension. I’d like to just also mention implementing aging diagnostics into clinical practice.

There are approximately 50 labs in the states that move into the right direction. They could do much more if they had more money.

Well, it’s all about the money, but not really big money.

Transhumanists from all over the world have been trying to solve the mystery of how to secure funding for reaching physical immortality. The very development of science leads towards it, but this process is too slow, a lot of people may not make it in time. Our goal is to accelerate.

Right now it has become obvious how to find the money for radical life extension. It’s crowdfunding. 200-300 campaigns need to be created on various crowdfunding platforms on the topics of fighting aging and regenerative medicine.

Of course, we may not be able to find the necessary amounts of money right away, but we will be able to delineate the scope of goals, most importantly not using just the general words, but particular scientists, labs and research plans.

Even by only preparing the campaigns we will influence the society by once again providing the proof of the possibility of significant life extension. Unfortunately, molecular biology is not part of an every day’s person background. We will make people more educated, show them how diseases originate, progress, and how they relate to aging. We will also tell the people what can be done.

While working on the crowdfunding campaigns we will mobilize our supporters by giving them a concrete tool and a plan of action. Fighting aging crowdfunding will become a very powerful transhumanist organizational solution.

In the end we will gather the money, implement our projects and win!

If you are interested in bringing this plan to live, let’s collaborate. Every single project requires a manager, analyst, scientist, director, operator, a guy who owns a car and a guy who writes a lot about this on the Internet. There is work for everybody, so let’s do this.


Filed under Policy

Full Genome Sequencing Costs

NGS full genome sequencing prices

For those who are interested how much it costs to get your full genome sequenced – the prices are above. This table comes from a great review article on cancer genome sequencing that I have written before. The table clearly illustrates the promise of next generation sequencing in terms of pricing. It’s getting more and more affordable. I think we will see full genome sequencing in the clinic as a routine diagnostic tool quite soon. This will mean more accurate diagnoses, hence better treatment for various diseases. Of course the application to cancer is the most obvious one when we can identify the genome mutations and changes in expression that lead to progression of the disease. More accurate diagnoses and treatments will increase health and longevity of millions of people.

Leave a comment

Filed under Uncategorized

Successful Results of Aging Research According to the Washington Post

It is always nice to see articles about fighting aging in the major press sources. This article in Washington Post sums the most promising results in aging research so far. The most successful interventions include caloric restriction, metformin, acarbose, rapamycin, genetic modification and GDF11/parabiosis. I would say that the author has left out some things like melatonin and aspirin, for example. Also I wouldn’t suggest parabiosis as an intervention, sure it’s good for the old, but what about the young organisms? Some of their biological parameters become worse as a result of parabiosis. We wouldn’t want that effect in people, would we?)) However, pharmacological intervention based on the GDF11 is another thing that may work.

I was very pleased to see that gene therapy was among the proposed solutions. In my opinion it has enormous potential. We now know about 100 longevity-associated genes. Why not use gene therapy to either bring these genes into the organism, or increase their efficiency if they already exist. We could try various combinations of those genes and maybe the combinations can lead to synergistic rather than additive effect. But who am I kidding, additive effect would also be amazing if proven safe and efficient in humans.

Leave a comment

Filed under Life Extension