I just couldn’t walk past this article in PNAS about the miracles that happen to one strain of lab mice – MRL. These guys can fully close ear holes made for labeling purposes in order to mark a mouse for its whole life; in these animals the holes turn out to be just temporary. The wounds close without scarring, and brand new cartilage, derma, epidermis and hair are formed. And the rest rest of the mice could wear earrings, if only there were any animal jewellery!
Another striking thing is that this feature was noticed 9 years ago, when the same group of researches published a paper telling how MRL mice can heal wounds on their hearts, leaving hardly any scars. As early as in 2001, it was shown that these mice can heal themselves from myocardial infarction after-effects in 60 days. But for some reason the molecular mechanisms underlying these miracles haven’t been studied until now. So, here they are.