Can We Live Forever – Artificial Organ Regrowth


Regenerative medicine has the potential of being the first solution to the problem of aging. In several years we’ll be able to repace damaged or diseased organs with the new grown ones. The video shows how it can be done. I found the story about the decellularized rat heart scaffold amazing. They actually show what a scaffold looks like and it’s beautiful.

 

Advertisements

20 Comments

Filed under Regenerative medicine

20 responses to “Can We Live Forever – Artificial Organ Regrowth

  1. Pingback: Can We Live Forever – Artificial Organ Regrowth (via Maria Konovalenko) | Business, Technology and the Future

  2. Suddenly scaffolds have become a lot more interesting, and I did not even realize we had them. Thanks for sharing this.

    • You are very welcome. You’re right. It’s actually not obvious that it’s the scaffold that defines the geometry of an organ, but not the cells. And cells have complex interactions with scaffolds. One of the ways to regulate behavior of cells is to add specific molecules to scaffolds, like growth factors, that would either “tell” the cell to devide, or would attract more cells to stick to the surface.

  3. Hi, Maria.

    As one who recently had to have a temporary diverting colostomy, due to long-standing severe Crohn’s disease / intestinal fibrosis, I’m interested to know how long you think it will be before this technology can replace, say, a rectum? Some colonic fibrosis has already been reversed in mice, using high-dose extracts of boswellia and scutellaria, but this kind of treatment, thanks to lack of funding and the FDA, will probably never be available for humans. Realizing that the rectum is more complex than a windpipe, I can’t see rectal replacement happening anytime soon, but I’d love it if you’d tell me differently. I appreciate any response you might give.

    Thanks,
    Jason

    • Hi Jason,

      I don’t think it will take more than five years or so. This estimate originates from the general trends in regenerative medicine. I am talking about the therapy in a lab or experimental clinical procedure. Certainly it will take some more time for the FDA to approve it. Unfortunately, I don’t know who is working on rectal replacement in particular, but I’m sure large centers like Wake Forest Institute for Regenerative Medicine and University of Pittsburg already have or will in the nearest future include rectum in the list of organs on which they are working on. You can help the situation your self, actually. You can do the research, find out who’s doing what in this area and either contact the researchers and ask them questions and tell them about the importance of the problem. Also blogging always helps. If you write a blog on this particular topic it may become the start of growing interest, maybe a community or patients needing the not yet existing procedures. You can form the demand your self and formulate the task for the researchers and funding agencies. I think you should give it a try, because there’s always a chance you can speed things a little.

      Cheers,
      Maria

  4. Thanks, Maria, for the response. I did actually try to contact Dr. Paolo Macchiarini, but he never got back to me — he was probably out saving someone’s life. Or perhaps the word ‘rectum’ made him feel icky? Anyway, I’ll keep trying. And if I can restore the rectum to health on my own, I won’t NEED a replacement. Then life will be good again and I won’t have to say rectum anymore. 🙂

    Jason

  5. kyle

    How long do you think it will be untill we live forever

    • That’s a very good question, Kyle.

      My answer is – it depends on research funding. The more money goes to studying epigenetic mechanisms of aging, regenerative therapies, mathematical modeling, neuroscience, the faster we’ll have radical life extension methods available.
      I believe it will be possible in the 21st century. The only remaining question is wherther this will be in 30 years or in 70. This depends solely on us. I encourage everyone to promote life extension, because the more people say it is necessary, the fasterwe’ll have it.

  6. Kyle

    Then you should try to make a law where everyone in the world has to give you $10 for research and funding for the medicine and that should be plenty of money and the medicine should be here in about 2 years

    • Yes, that would be perfect. As difficult as it sounds, it acually is doable. We have to choose the right country first, probably something like Latvia or a similar small European country, which could serve as an example for bigger ones and have a vote in the European Comission. Oh, and that would also cost quite a bit)

      • Kyle

        It would cost alot but it would be worth it you could live forever and never have to stress about dieing of course people could die from stuff we cant prevent like natural disasters or fires but living forever would benifite us in some much ways

  7. You are absolutely right. The faster we develop the therapies the more people will be saved.
    I have to stress that every day 100,000 people die from aging. If you multiply this number by the amount of days the resulting amount of aging victims is overwhelmingly scary. 1 year equals 36,500,000 – that’s like 1 Shanghai and 1 Moscow, or 4 New Yorks.

    • Kyle

      Also we would solve aging so if you wanted you could be 21 forever it would also help because you would never have the fear of losing a family member again

        • kyle

          Then we need to start researching now

          • There’s research going on, but the problem is that the amount of funding for this type of research is scarce. So we really need to advocate increase in money spent on regenerative medicine and other kind of anti-aging research. I look forward to people joining me in this endeavor. Everyone can help at least by talking to their friends, colleagues, facebook friends about how important aging research and regenerative medicine is. Reposting can also help a lot.

  8. Kyle

    if you had to guess without funding how long would it take to have this medicine

  9. Tulsi

    Hi Maria,
    I just want to know exactly when organs will be on shelves as it were, and be in use and what kinds of trials need to be approved. I know some people are being saved, as single experiment cases or a group of 30 people but when can it go large scale?

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s