I found it quite interesting that mutations in multiple myeloma are located in the genes involved in NFkB pathway. This chain of events in the cell activates as a response to various kinds of stress, such as cytokines, free radicals, ultraviolet irradiation and other stressors. NFkB is a transcription factor which is responsible for activating genes linked to increased inflammation. Multiple myeloma genome sequencing revealed that this molecular pathway is altered. So apparently there’s a link between the aberrant activity of NFkB and cancer, and I would like to point out that there’s probably a link to aging as well. It is most likely that inhibition of this pathway may lead to cancer incidence reduction and also anti-aging effects. It has already been shown that pharmacological blocking of NFkB pathway prolongs lifespan in drosophila. Read the paper by Dr.Alexey Moskalev who’s done this experiment.
Maria Konovalenko 
Maria:
You might find this blog post interesting as well:
http://math-blog.com/2011/10/07/tackling-cancer-with-math
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