While discussing the longevity gene therapy project we encountered various questions and observations that prompted us to broaden the project and slightly change it. Generally, all the comments can be reduced into 5 main points:
- You need to enlarge the list of therapeutic genes by adding to it this and that.
- You want to use too many genes; therefore you need to make the project simpler by keeping only the most effective genes
- If you apply all the genes at the same time, some of them may cancel out the effects of other genes.
- Will it be safe to use viral vectors to deliver genetic constructs?
- How safe are therapeutic genes for the body?
Some of the observations were of completely opposite nature, so we decided to do 2 versions of the project. One of them is for aging geneticists. In it we almost double the list of the genes extending lifespan. This project will allow testing many poorly studied genes, but promising in terms of aging. Besides, some unexpected results can be obtained, which is always valuable.
Please welcome the updated Human Physical Immortality Roadmap. This is the first part where we look at the evolution of biotechnologies that will lead to significant lifespan extension in humans. The whole sequence of steps will yield the best result, but of course each individual step has the potential to become quite important in improving human condition, for example developing the biomarkers of aging and longevity. One of the goals of this roadmap is to clearly illustrate the feasibility of those technological advances that will save us from the debilitating diseases of old age and buy us the precious time to live our lives the way we like.
The other 6 parts of the Roadmap: Regenerative Medicine, Digital Immortality, Cryonics, Cyborgization, Nanomedicine, and Artificial Intelligence.
One of the best conferences in the world, Genetics of Aging and Longevity conference, will take place on April 6-10 in Sochi, the city of 2014 Olympic Games. A couple of words about the event – the best geneticists of aging will gather to share their latest research on
- Longevity genes in human and animals
- Epigenetic mechanisms of aging
- Inflammation and hyperfunction, intertwined mechanisms of aging?
- Environment, genes and aging
- Biomarkers of biological age
- Pharmacological interventions in aging
- Strategies for regenerative medicine applied to humans
- Systems biologyof aging and longevity
- Comparative biology of lifespan
- Oxidative damage and aging
And now we know the place where the magic will happen – Radisson Blu Resort & Congress Center. Here are the pictures of the place.
Don’t forget to register for Genetics of Aging and Longevity here
Dr. Reis talks about the main trends in longevity research, potential for creation life extension therapies in the nearest future, his favorite genes, preferable ratio of basic to applied research funding and the overall hurdles of aging research field.